ARNAB GUPTA

Principal Investigator

Arnab completed his PhD in 2006-07 from CSIR-Indian Institute of Chemical Biology in the filed of human genetics under the supervision of Prof. Kunal Ray. Subsequently, he moved to US for his postdoctoral training with Profs. Svetlana Lutsenko and Ann Hubbard at The Johns Hopkins University. His field of study was to elucidate the regulations of the human copper pumps and channels. After a brief stint at the University of Calcutta as a Ramanujan Fellow, he set up his independent research group at IISER Kolkata. Presently at IISER Kolkata, using various cutting edge techniques especially high-resolution imaging and molecular dynamic studies, his group is probing the secretory pathway that the copper ATPase ATP7A and ATP7B traverses to export copper from the cell. The second line of the group's interest is to understand the copper mediated endocytic regulation of the primary copper importer CTR1. The research of the group is funded through multiple funding agencies, i.e., The Wellcome Trust DBT India Alliance, DST-Early Career Research Award, Intramural funding from IISER Kolkata. 

Salauddin Sekh

Lab Manager

I oversee all the macro as well as micro managements in Arnab's Lab. In my leisure time I help others in their experiments.

Ruturaj

Int. Ph.D. Fellow

I am interested in differential i.e Apico-Basolateral trafficking of copper transporters ATP7B and ATP7A in polarized epithelial cells. I am also interested to understand the role of copper transporters in drug resistance against cancer.

Indira Bhattacharya

Junior Research Fellow

I am interested in studying the role of lysosomes in maintaining copper homeostasis.  

Samarpita Sen

BS-MS Student (4th Year)

I study the regulation of copper transporters using MD simulation.

Santanu Das

Junior Research Fellow

I am investigating novel regulatory mechanisms of the human copper transporter ATP7B in hepatocytes.

Saptarshi Maji

Junior Research Fellow

I am trying to find the cue that leads to internalization of CTR1.

Soumyendu Saha

BS-MS Student (5th Year)

I am interested in apical trafficking of copper transporter ATP7B.

Sumanta Kar

Junior Research Fellow

A membrane protein is escaping its location under certain conditions; the localization and nature of the protein inside the cell is very suspicious and uncanny. The edicting portion of the protein of any helping partners may modulate in this deportment of the protein. My act in this situation is to investigate the fine tuners and to find the informers helping the protein in this escape.

Rupam Paul

Junior Research Fellow

I joined Arnab's lab recently. I am still figuring out my topic of interest. In the mean time i am interested in studying involvement of copper transporters as defence mechanism of host against pathogens.

Prodyuti Sarkar

BS-MS Student (5th Year)

I am working on microfabrication of SOMs. I am trying to create nano channels on SOMs coated glass surface.

COPPER METABOLISM

AND MEMBRANE TRAFFICKING LAB

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