ARNAB GUPTA
Principal Investigator
Arnab completed his PhD in 2006-07 from CSIR-Indian Institute of Chemical Biology in the field of human genetics under the supervision of Prof. Kunal Ray. Subsequently, he moved to US for his postdoctoral training with Profs. Svetlana Lutsenko and Ann Hubbard at The Johns Hopkins University. His field of study was to elucidate the regulations of the human copper pumps and channels. After a brief stint at the University of Calcutta as a Ramanujan Fellow, he set up his independent research group at IISER Kolkata. Presently at IISER Kolkata, using various cutting edge techniques especially high-resolution imaging and molecular dynamic studies, his group is probing the secretory pathway that the copper ATPase ATP7A and ATP7B traverses to export copper from the cell. The second line of the group's interest is to understand the copper mediated endocytic regulation of the primary copper importer CTR1. The research of the group is funded through multiple funding agencies, i.e., The Wellcome Trust DBT India Alliance, DST-Early Career Research Award, Intramural funding from IISER Kolkata.
Salauddin Sekh
Lab Manager
I oversee all the macro as well as micro managements in Arnab's Lab. In my leisure time I help others in their experiments.
Santanu Das
Senior Research Fellow
I am investigating regulatory mechanisms of the human copper transporter ATP7B in hepatocytes.
Sumanta Kar
Senior Research Fellow
I study on the regulatory mechanisms of Human Copper Transporter 1.
Sharon Mary Jose
Junior Research Fellow
I am trying to find out cues involved in Inter-domain interaction of ATP7B and its importance in Copper dependent trafficking.
Raviranjan Pandey
Junior Research Fellow
I joined Arnab's Lab recently. Still exploring Ideas
Samarpita Sen
BS-MS Student (5th Year)
I study the regulation of copper transporters using MD simulation.
Taniya Mandal
BS-MS Student (5th Year)
I am studying the effects of Wilson disease mutations w.r.t. its copper export and trafficking in polarized epithelial cells.
Ankita Nayak
BS-MS Student (5th Year)
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Ruturaj
Int. Ph.D. Fellow
I am interested in differential i.e Apico-Basolateral trafficking of copper transporters ATP7B and ATP7A in polarized epithelial cells. I am also interested to understand the role of copper transporters in drug resistance against cancer.
Saptarshi Maji
Senior Research Fellow
I am trying to find the cue that leads to internalization of CTR1.
Rupam Paul
Junior Research Fellow
I am interested in studying involvement of copper transporters as defence mechanism of host against pathogens.
Pruthwiraj
Research Assistant
I am working on therapeutic aspects of Wilson's disease.